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Also
called sabal palm, grows in the southeastern United States. Its dark berries
were traditionally made into a tea and taken for urinary problems or sexual
difficulties. During much of the nineteenth century, saw palmetto berry extract
was included in the National Formulary, a list of acceptable medicines, to
treat the symptoms of prostate enlargement. As medicine came to rely more on
science, doctors became skeptical about the value of this botanical remedy and
it was dropped from the Formulary before 1950. More recent studies indicate
that it is indeed effective for this indication and probably should never have
been dropped.
Even those who have saw
palmetto growing in their backyards may want to stick with commercial extracts
rather than try to make their own tea. The berries do not taste good, and most
of the active ingredients appear to be less soluble in water than in alcohol or
hexane.
Saw
palmetto berries contain free fatty acids and plant sterol compounds described
as phytosterols or sitosterols, especially beta-sitosterol and some related
chemicals. These ingredients appear to modify estrogen receptors and block the
conversion of testosterone to dihydrotestosterone (DHT), a more active
chemical. There are also flavonoids and some polysaccharides in the berries,
but their activity has not been described. Standardized products contain 85 to
95 percent fatty acids and sterols.
At
least seven controlled studies demonstrate that saw palmetto berry extract is
better than placebo for treating symptoms of benign prostate hypertrophy
(frequent urination, restricted urine flow, nighttime urination). In one study,
the herb was nearly as effective as the prescription drug Minipress (prazosin)
for controlling such symptoms, and in other research it reportedly performed
better than the prescription prostate medicine Proscar (finasteride) in
reducing symptoms. Research using ultrasound has shown that saw palmetto berry
extract can shrink enlarged prostate tissue. Some research has shown
that saw palmetto berries may also have anti-inflammatory activity and can help
reduce allergic reactions. The plant has been used traditionally as a diuretic
and may also help to stimulate immune response. The herb's effect on enlarged
prostate tissue is by far the most clinically important.
For
early stages of benign prostate enlargement: 320 mg extract daily, in divided
doses, or the equivalent of 1 or 2 grams of saw palmetto berries. Four to six
weeks may be required to determine if the herb is
helping.
Special Precautions: Estrogen-like activity and the ability to
block testosterone conversion suggest that pregnant women and those who may
become pregnant should avoid contact with saw palmetto berry extract, just as
they should avoid finasteride. Men are urged not to treat urinary symptoms
without medical diagnosis. Similar symptoms might be caused by a more serious
condition, such as prostate.
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